Madhumitha is born and brought up in Pudhukottai. Madhumitha has two siblings; Lokesh, a brother and a sister named Sripriya. Madhumitha is a B.com graduate. Madhumitha made her acting debut with
” serial in Sun TV, directed by
." She played the role, Velvizhi and impressed the audience.
After this serial, she got an opportunity to play in a serial, Kadal Kadandhu Uthyogam, telecasted in Raj TV. She had also played in
, a serial in Sun TV directed by Kula Deivam director Thiru Murugan. She has been playing the role Arthi in Aranmanai Kili, a serial telecasted in Vijay TV directed by Anil Rao.