Isaac Varghese is an Indian actor born in Chennai, Tamil Nadu. He finished his optional training at KVHVF School, Chennai. He has a four-year college education from Madras Christian College, Chennai. Issac made his acting introduction in the Tamil movie "Gemini" alongside Kiran Rathod, coordinated by Saran and delivered by B.Gurunath. He additionally acted with surely understood entertainers like Shwetha Bandekar, Nagashree, Sree Vani, Gayathri, Neelima Rani, and Srithika. He has shown up in some outstanding movies, for example, Gemini, Idhaya Thirudan and Singam II.

His exhibitions in numerous films were commended particularly in "Idhaya Thirudan" which was a standout amongst the Best movies of the year 2006. He worked with a portion of the top names of that time like Issac in "Singam II" alongside Suriya, Anushka Shetty, Hansika Motwani , and Yuvarani. Isaac Varghese as of now doing the negative role in Perazhagi sequential alongside Porkodi in Colors Tamil and supporting job in Kalyana Parisu 2 sequential alongside Mona Bethra in Sun TV.