Madan Tyagi made his maiden appearance in Hindi TV serial industry in 2010 with a negative role. He appeared as Vishnu Pandey in Zee TV serial 'Bhagon Wali baante Apni Taqdeer' . The serial was produced by Samidha Khalid for Creative Lab. The story was written by Samidha Khalid with others and it was directed by K.
Mohit Kumar Jha
. It was the story of a girl who brings luck to the place wherever she goes but her own life is never happy or peaceful. Madan acted as the youngest son of Pandey family who is a criminal lawyer by profession and is always busy in creating his network for fulfilment of his dream of becoming a politician as well as improvement in his profession which in any case is not going very smooth. He is not having good relations with his wife and often beats her to keep her under control. But his wife Kalsanwali (played by Shruchi verma) is also equally aggressive and reacts with the same aggression. Later on, he also acted as Vinod Goyal in Masakali which was telecast on Sahara One.
The performance of Madan Tyagi was highly praised and the serial was also nominated for Zee TV Rishtey Awards for the best player in a negative role. Now Madan Tyagi is a revered name for negative roles. He is also very active in Mumbai theatre and has performed in many plays like P Se PM Tak, Dulari Dhamal etc.