Top Companies In Genomics

Modern science has introduced a range of technological advancements that has made it possible to execute actions that were once considered challenging. One such area of study is Genomics that has recently experienced growth.

Genomics is the study of an organism’s DNA. Genes are a crucial part of our DNA. Genomics involves studying a living being’s entire DNA to identify gene functionality and its interaction with other genes. The genome consists of both code genes and non-coded DNA. Healthcare professionals utilize Genomics to conduct various researches and discover treatments for severe conditions like cancer and Alzheimer. It is also utilized to develop life-saving drugs and conduct research in agricultural industry.

Rising support from government and private sector has led to the growth of Genomics industry. Genomics incorporates three major components:

• Zinc-finger nucleases or ZFN
• transcription activator-like effector nucleases or TALEN
• clustered regularly interspaced short palindromic repeats-associated protein nine or CRISPR-Cas9

Using above components, researchers can reverse life-threatening genetic diseases.

One example of a genetic disorder is sickle cell disease. With the help of CRISPR-Cas9, researchers edit stem cells from patient’s genes to develop fatal haemoglobin that can successfully replace mutated cells and reverse the condition. Genomics is utilized mainly in hospitals and private research labs to analyze an organism’s biological system and solve complex genetic problems.

Many multinational companies are coming forward to invest in the industry. They utilize a combination of genomics apps and tests to discover DNA alterations. Companies are investing in Genomics to identify rare diseases and develop life-saving drugs. Many public sector companies are investing in microarray and DNA technology. Recently, many leading companies are investing in Genomics, contributing to the growth of the healthcare sector in the years to come.

We have shortlisted the Top 10 companies in Genomics known for their contribution to the healthcare industry.

1. Illumina

Illumina is a strong player in the genomics industry known for genome sequencing( a method that determines the entire genetic composition of a particular organism or cell type) and genotyping products. The company conducts clinical research related to reproductive health, genetics, and rare diseases. They identify and analyze genomic data to improve cancer diagnosis. Their focus is to detect cancer genomes in early stages and access tumour data in real-time. Illumina offers microarray tools to examine variation in genetics.

2. Genscript Biotech Corporation

Genscript Biotech Corporation is a biotech company with headquarters in China. The company offers innovative gene synthesis products and genomic editing materials. Recently, in 2023, Genscript collaborated with a biotech firm to develop cell-based treatments for tumours. Their service list includes Gene, Oligo, CRISPR, Peptide, Protein, Reagent antibodies, and others. Genscript offers comprehensive research tools for SARS-Cov-2, western blotting, developing antibodies for cancer treatment, and Claudin 18.2 drug.

3. BGI Genomics

BGI Genomics is headquartered in China and offers a wide range of services including genotyping, sequencing, and gene analysis. The company sequences the genomes of humans, animals, plants, and other microorganisms. BGI is actively engaged in animal cloning( a process in which animals are reproduced with identical genomes, either by natural or an artificial method), health testing, and contract research. During Covid, the company launched its fluorescent RT-PCR kit to help trace the SARS-Cov-2 virus.

4. PacBio

Pacific Biosciences(PacBio) is famous for developing long-read sequencing technology. The company executes complete genome sequencing in a single pass. Their technology is used in various applications, including research and diagnostics. Their sequencing technology offers an intricate view of genomes, epigenomes, and transcriptomes. The targeted sequencing identifies all types of genetic variations accurately, including those found in the extreme regions of genome.

5. Thermo Fisher Scientific

Thermo Fisher Scientific offers scientific instruments, equipment, and consumables. Their products are widely utilized for developing drugs and other healthcare products. The company provides real-time PCR-based testing solutions to detect pathogens of infectious diseases. Thermo Fisher encompasses a vast library of predesigned Applied Biosystems assays to trace pathogenic organism targets for clinical testing and researching communicable diseases. They offer PCR-based solutions to identify diseases such as respiratory, urinary, sexually transmitted, HIV, and gastrointestinal infections.

6. Krystal Biotech

Krystal Biotech specializes in developing therapeutic genes. The genes are injected directly into the patient’s cell for fast recovery. Their goal is to develop genetic medicines using redosable gene therapies and offer it to patients with rare and life-threatening diseases. Krystal’s HSV-1 technology enables delivering genes to treat patients having medical conditions with limited treatment options. The HSV-1 technology ensures safe delivery of genetic material and increased payload capacity.

7. NeoGenomics

NeoGenomics offers services for cancer testing. The company designs a therapy selection panel for early-stage cancer patients. It helps in timely diagnosing and preventing fatal condition. They empower oncologists, pathologists, and pharma companies to ensure the best care for patients. Precision oncology is their core service. NeoGenomics portfolio includes broad-panel DNA and RNA-based next-gen sequencing. They offer personalized care services for cancer patients such as therapies and clinical trial matching.

8. Agilent Technologies, Inc

Agilent Technologies is a leading company specialized in fields of life science, diagnostics, and applied markets. The company provides services in the fields of food, pharmacy, chemical and energy, and environment and forensics. Agilent offers a comprehensive set of technologies, including bioreagents, gas and liquid chromatography, immunohistochemistry, microarrays, and more. The company invests in R&D with an aim to make advancements in the fields of life sciences, diagnostics, and chemical analysis. Agilent’s digital lab promotes sustainability by optimizing the utilization of instruments within the lab, thereby lowering energy consumption.

9. Oxford Nanopore Technologies

Oxford Nanopore Technologies, headquartered in UK, is known for developing world’s first nanopore sequencing technology. The nanopore technology ensures real-time data delivery, scalability, and thorough analysis of biological data. Oxford’s nanopore technology is utilized for drug development, conducting research, and diagnostics. The platform offers you a detailed view of the genetics of human disease and allows you to access sequencing data from DNA and RNA molecules in a single platform.

10. Ginkgo Bioworks

Ginkgo Bioworks is a US biotech company, known for developing thousands of genome edits to analyze the E.Coli bacteria. With the help of genetic engineering, bacterias are developed for industrial applications. The company offers a comprehensive range of services including enzyme designing, metabolic engineering, strain optimization, and biosecurity services. The company develops probiotic bacteria with the help of biology to offer solutions for treating various life-threatening diseases. Gingko also provides biosecurity and biodefense solutions to respond quickly to future biological threats.