Vandana Vithlani is best known as Urmila of Saath Nibhana Saathiya serial which is aired on Star Plus. In this serial, she is playing a fashionable and greedy middle class lady who wears loud make up and always keeps on planning something devilish. Viewers love her comic performance in the show. She was nominated for the award of Favourite Mazedaar Sadasya for her comic role of Urmila in Saath Nibhana Saathiya. In 2012, Vandana Vithlani was also seen in Nayi Soch Ki Talaash Aamir Ke Saath.

Vandana Vithlani was born on 26 January and she did her schooling from New Era High School and completed her higher studies from Jai Hind College, Mumbai. She is married to actor Vipul Vithlani and has two sons. Before marriage, her surname was Botadkar. She is a fun loving person, who believes in living life to the fullest and enjoys being a part of Saath Nibhaana Saathiya.