Moeen Khan and Syed Bibi gave birth to Yasmeen in 1950 as Shamshad in Kakshal, Peshawar. Her family relocated to Karachi in the 1960s, where she was able to sign on for a part in the first movie of her career. Yasmeen quickly rose to cinematic fame and gained notoriety as an actor. Yasmeen Khan's career was established when she took the lead in Yousaf Khan Sherbano, the first successful Pashto film, which was released in December 1970. Yasmeen co-starred in movies with Pashto actor
, and the two of them rose to fame. Together with Badar Munir, she appeared in more than 80 Pashto films, totaling 200 throughout the course of her acting career. Yasmeen Khan's debut Urdu film, Dulhan Ek Raat Ki, was released in 1975. Yasmeen left the entertainment industry and became more religious. She was killed on April 15, 1999.